At latest update no published data on excretion into breast milk were found.
It has a negligible systemic absorption through skin or nails, which highly interfere with excretion into breast.
It has been described sporadic neonatal use without observing side effects.
Until more published information about this drug regarding breastfeeding appears, it may be preferable a known and safer alternative (topical Terbinafine, Floconazole), especially during the neonatal period and in cases of prematurity.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
- Amorolfine Hydrochloride
- Αμορολφίνη (Greek)
- أمورولفين (Arabic)
- Аморольфин (Cyrillic)
- 阿莫罗芬 (Chinese)
- アモロルフィン (Japanese)
- C21H35NO (Molecular formula)
Drug trade names
- Fu M, Ge Y, Chen W, Feng S, She X, Li X, Liu W. Tinea faciei in a newborn due to Trichophyton tonsurans. J Biomed Res. 2013Abstract
- Polak A. Kinetics of amorolfine in human nails. Mycoses. 1993Abstract
- Franz TJ. Absorption of amorolfine through human nail. Dermatology. 1992Abstract
- Roncari G, Ponelle C, Zumbrunnen R, Guenzi A, Dingemanse J, Jonkman JH. Percutaneous absorption of amorolfine following a single topical application of an amorolfine cream formulation. Clin Exp Dermatol. 1992Abstract