Fesoterodine
Antimuscarinic agent with atropine-like action. It is metabolized in Tolterodine
At latest update no published data on excretion into breast milk were found.
Until more published data on this drug in relation to breastfeeding is available, a known safer alternative as Tolterodine should be preferred with more favorable pharmacokinetics characteristics for lactation (e.g. high protein-binding capacity, faster elimination and lower oral bioavailability), particularly during the neonatal period and prematurity case.
Take as smallest dose as possible and avoid long-term use since anticholinergics can reduce milk production.
Monitoring anticholinergic symptoms in infants (dry mouth, constipation ..) is warranted.
Alternatives
- Tolterodine Tartrate (Low Risk probable)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Fesoterodine Fumarate
Writings
- فيزوتيرونيد (Arabic)
- Фезотеродин (Cyrillic)
- 非索罗定 (Chinese)
- フェソテロジン (Japanese)
- C26H37NO3 (Molecular formula)
Drug trade names
References
- EMA. Fesoterodina. Ficha técnica. 2014 Full text (in our servers)
- EMA. Fesoterodine. Drug Summary. 2014 Full text (in our servers)
- Bizzarro A, Iannucci F, Tolino A, Soricelli A, Guarino G, Verdoliva A. Inhibiting effect of atropine on prolactin blood levels after stimulation with TRH. Clin Exp Obstet Gynecol. 1980Abstract