Drug is secreted in high amount into breast milk.
Several cases have been published that did not report side effects in nursing babies, however, hypotension, bradicardia and tachypnea were found in one newborn.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Drug trade names
- Anderson PO. Treating Hypertension During Breastfeeding. Breastfeed Med. 2018Abstract
- Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. 2013Abstract
- Ghanem FA, Movahed A. Use of antihypertensive drugs during pregnancy and lactation. Cardiovasc Ther. 2008Abstract Full text (link to original source) Full text (in our servers)
- Hale TW. Medications in breastfeeding mothers of preterm infants. Pediatr Ann. 2003Abstract
- Eidelman AI, Schimmel MS. Drugs and breast milk. Pediatrics. 1995Abstract
- Boutroy MJ, Bianchetti G, Dubruc C, Vert P, Morselli PL. To nurse when receiving acebutolol: is it dangerous for the neonate? Eur J Clin Pharmacol. 1986Abstract
- Riant P, Urien S, Albengres E, Duche JC, Tillement JP. High plasma protein binding as a parameter in the selection of betablockers for lactating women. Biochem Pharmacol. 1986Abstract