Is Alcaftadine compatible with breastfeeding? Do we have alternatives for Alcaftadine?


December 19, 2013 (Very Low Risk)

Topical ophthalmologic anti-histaminic drug that achieves very low plasma concentration with only 60 pg/mL. Hence, an insignificant excretion into breast milk should be advanced.


We do not have alternatives for Alcaftadine since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names


  1. Bohets H, McGowan C, Mannens G, Schroeder N, Edwards-Swanson K, Shapiro A. Clinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitis. J Ocul Pharmacol Ther. 2011Abstract
  2. Alcaftadina. Ficha técnica. 2011 Full text (in our servers)
  3. Alcaftadine. Data Sheet. 2011 Full text (in our servers)