Allantoin
A uric acid derivative that is found in body fluids (urine, amniotic fluid, saliva) of certain animals (cows, snails) and plants (comfrey).
Uric acid is the final product from the degradation of purines in humans and primates that do not possess an enzyme which degrades uric acid to allantoin in other mammals and non-mammals.
Purines are very abundant in meats, entrails, fish, seafood and beer.
Allantoin is used topically as a cosmetic and in oral hygiene products. It has healing properties (PubChem 2017 7.1)
Since the last update date we have not found published data on its excretion in breastmilk.
The low plasma absorption of most topical dermatological preparations makes it unlikely that it will transfer to breast milk in significant amounts.
There is no known toxicity (Akema 2012).
Do not apply on the chest in order to prevent the infant from ingesting it; if necessary, apply after breastfeeding and clean well with water before the next feed.
Alternatives
We do not have alternatives for Allantoin since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- 5-Ureidohydantoin
- Glyoxyldiureide
Writings
- Αλλαντοΐνη (Greek)
- Аллантоин (Cyrillic)
- アラントイン (Japanese)
- C4-H6-N4-O3 (Molecular formula)
- 2,5-Dioxoimidazolidin-4-ylurea (Chemical name)
- 5-Ureidohydantoin (Chemical name)
- 5-Ureidoimidazolidine-2,4-dione (Chemical name)
Drug trade names
References
- PubChem. Allantoin. PubChem.com 2017 Full text (link to original source) Full text (in our servers)
- AKEMA. Alantoína. Ficha técnica. 2012 Full text (in our servers)