Is Allopurinol compatible with breastfeeding? Do we have alternatives for Allopurinol?

Allopurinol

August 12, 2014 (Very Low Risk)

Anti-gout medicine also used along with Itraconazole for Chagas disease (american trypanosomiasis).

The amount excreted into breast milk is minimal with no effect on the infant.

American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Alternatives

We do not have alternatives for Allopurinol since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  2. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001Abstract Full text (link to original source) Full text (in our servers)
  3. Kamilli I, Gresser U. Allopurinol and oxypurinol in human breast milk. Clin Investig. 1993Abstract
  4. Kamilli I, Gresser U, Schaefer C, Zöllner N. Allopurinol in breast milk. Adv Exp Med Biol. 1991Abstract