Is Alpha-Galactosidase compatible with breastfeeding? Do we have alternatives for Alpha-Galactosidase?

Alpha-Galactosidase

December 19, 2013 (Very Low Risk)

Enzymatic protein for sustitutive therapy of Fabry’s disease.

Also orally used as anti-flatulent.

Its high molecular weight and protein structure make excretion into breast milk or oral absorption by the infant unlikely.

Alternatives

We do not have alternatives for Alpha-Galactosidase since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Alpha-Agalsidase

Drug trade names

References

  1. Di Stefano M, Miceli E, Gotti S, Missanelli A, Mazzocchi S, Corazza GR. The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms. Dig Dis Sci. 2007Abstract
  2. Ganiats TG, Norcross WA, Halverson AL, Burford PA, Palinkas LA. Does Beano prevent gas? A double-blind crossover study of oral alpha-galactosidase to treat dietary oligosaccharide intolerance. J Fam Pract. 1994Abstract
  3. Smiley KL, Hensley DE, Gasdorf HJ. Alpha-galactosidase production and use in a hollow-fiber reactor. Appl Environ Microbiol. 1976Abstract