Is Alvimopan compatible with breastfeeding? Do we have alternatives for Alvimopan?

Alvimopan

December 19, 2013 (Low Risk)

It is a μ-opioid receptor antagonist that accelerates intestinal transit. Prescribed after intestinal surgery procedures.

Since oral absorption and plasma levels are very low secretion into breast milk is thought to be minimal.

Alternatives

We do not have alternatives for Alvimopan.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. Hussar DA. New drugs 09, part 1. Plast Surg Nurs. 2009Abstract
  2. Alvimopan Data Sheet (Drugs.com) 2009 Full text (in our servers)
  3. Foss JF, Fisher DM, Schmith VD. Pharmacokinetics of alvimopan and its metabolite in healthy volunteers and patients in postoperative ileus trials. Clin Pharmacol Ther. 2008Abstract