Is Anagrelide-Hydrochloride compatible with breastfeeding? Do we have alternatives for Anagrelide-Hydrochloride?

Anagrelide-Hydrochloride

December 22, 2013 (High Risk)

On latest update relevant data on breastfeeding were not found.

Since it is usually prescribed for long-term treatment and it does not have a low oral bioavailability, infant coagulation could be affected.

Potential adverse effects would be minimized by delaying nursing for 4-5 hours after last dose and checking-up for infant platelet count.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. Ramirez G, García-Sanchez R, Plaza S. [Management of patients with essential thrombocythemia]. Med Clin (Barc). 2013Abstract
  2. EMEA Anagrelida Ficha técnica 2009 Full text (in our servers)
  3. EMEA Anagrelide Data Sheet 2009 Full text (in our servers)