Is Armodafinil compatible with breastfeeding? Do we have alternatives for Armodafinil?

Armodafinil

June 30, 2015 (High Risk)

Used for treatment of narcolepsy.

On latest update relevant data on breastfeeding was not found.

Pharmacokinetic data indicates that drug excretion into breast milk would be significant.

Until more information concerning breastfeeding is available, a safer alternative is preferred.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • أرمودافينيل (Arabic)
  • 阿莫非尼 (Chinese)
  • Армодафинил (Japanese)

References

  1. Calvo-Ferrandiz E, Peraita-Adrados R. Narcolepsy with cataplexy and pregnancy: a case-control study. J Sleep Res. 2018Abstract
  2. Armodafinilo Ficha técnica 2010 Full text (in our servers)
  3. Armodafinil Data Sheet 2010 Full text (in our servers)
  4. Hoque R, Chesson AL Jr. Conception, pregnancy, delivery, and breastfeeding in a narcoleptic patient with cataplexy. J Clin Sleep Med. 2008Abstract Full text (link to original source) Full text (in our servers)
  5. Wise MS, Arand DL, Auger RR, Brooks SN, Watson NF; American Academy of Sleep Medicine. Treatment of narcolepsy and other hypersomnias of central origin. Sleep. 2007Abstract Full text (link to original source) Full text (in our servers)
  6. Spigset O, Brede WR, Zahlsen K. Excretion of methylphenidate in breast milk. Am J Psychiatry. 2007Abstract Full text (link to original source) Full text (in our servers)
  7. Heikkinen T, Ekblad U, Palo P, Laine K. Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation. Clin Pharmacol Ther. 2003Abstract