Is Articaine compatible with breastfeeding? Do we have alternatives for Articaine?

Articaine

January 7, 2014 (Very Low Risk)

On latest update relevant data on breastfeeding was not found.

Similar chemical structure to Lidocaine which is excreted into breast milk in minimal amount.

Anesthetic drugs for topical use both dermatological and odontological have almost nil absorption when properly used.

Alternatives

We do not have alternatives for Articaine since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Carticaine

Drug trade names

References

  1. Nizharadze N, Mamaladze M, Chipashvili N, Vadachkoria D. Articaine - the best choice of local anesthetic in contemporary dentistry. Georgian Med News. 2011Abstract
  2. Oertel R, Rahn R, Kirch W. Clinical pharmacokinetics of articaine. Clin Pharmacokinet. 1997Abstract
  3. van Oss GE, Vree TB, Baars AM, Termond EF, Booij LH. Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration. Eur J Anaesthesiol. 1989Abstract
  4. Van Oss GE, Vree TB, Baars AM, Termond EF, Booij LH. Clinical effects and pharmacokinetics of articainic acid in one volunteer after intravenous administration. Pharm Weekbl Sci. 1988Abstract