Is Asenapine compatible with breastfeeding? Do we have alternatives for Asenapine?
Asenapine
December 22, 2013 (Low Risk)
On latest update relevant data on breastfeeding was not found.
Its high molecular weight and plasma protein binding make excretion into breast milk unlikely as has been shown for other related anti-psychotic compounds.
Alternatives
- Olanzapine (Very Low Risk)
- Quetiapine Fumarate (Very Low Risk)
- Risperidone (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
References
- Klinger G, Stahl B, Fusar-Poli P, Merlob P. Antipsychotic drugs and breastfeeding. Pediatr Endocrinol Rev. 2013Abstract
- Bartlett JA, van der Voort Maarschalk K. Understanding the oral mucosal absorption and resulting clinical pharmacokinetics of asenapine. AAPS PharmSciTech. 2012Abstract Full text (in our servers)
- EMEA Asenapina Ficha técnica 2012 Full text (in our servers)
- Asenapine Data Sheet 2012 Full text (in our servers)
- Howland RH. Update on newer antipsychotic drugs. J Psychosoc Nurs Ment Health Serv. 2011Abstract