Is Asparaginase compatible with breastfeeding? Do we have alternatives for Asparaginase?

Asparaginase

October 14, 2018 (High Risk)

Drug is cleared from the body in 5 half-lives elimination period.

Resuming breastfeeding is likely safe after 10 pump-and-dump days period. Pumping is important to keep milk production.

See below the information of these related products:

Alternatives

We do not have alternatives for Asparaginase.

Compatible. Not risky for breastfeeding or infant.

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Not recommended. Cessation of breastfeeding or alternative.

Stopenski S, Aslam A, Zhang X, Cardonick E. After Chemotherapy Treatment for Maternal Cancer During Pregnancy, Is Breastfeeding Possible? Breastfeed Med. 2017Abstract
Anderson PO. Cancer Chemotherapy. Breastfeed Med. 2016Abstract Full text (link to original source) Full text (in our servers)
Pistilli B, Bellettini G, Giovannetti E, Codacci-Pisanelli G, Azim HA Jr, Benedetti G, Sarno MA, Peccatori FA. Chemotherapy, targeted agents, antiemetics and growth-factors in human milk: how should we counsel cancer patients about breastfeeding? Cancer Treat Rev. 2013Abstract
Koren G, Carey N, Gagnon R, Maxwell C, Nulman I, Senikas V; Society of Obstetricians and Gynaecologists of Canada. Cancer chemotherapy and pregnancy. J Obstet Gynaecol Can. 2013Abstract Full text (link to original source) Full text (in our servers)
Jazz Pharm. Asparaginase. Drug Summary. 2009 Full text (in our servers)
FDA. EUSA Pharm. Asparaginase. Data Sheet 2009 Full text (in our servers)