Belladona
In herbal medicine the leaves of this plant that contains numerous alkaloids are used: l-hyoscyamine and atropine, scopolamine or hyoscine and, all of them potentially high toxic.
Traditionally used with poor clinical evidence based on trials as anti-asthmatic, for common colds and intestinal spasms.
At latest update no published data on excretion into breast milk were found.
With anticholinergic and antimuscarinic properties that may reduce milk production: if necessary take as low dose as possible and avoid long-term treatment if decreasing milk production is observed.
Serious side effects (tachycardia, thirst, fever, mydriasis, seizures, coma), especially in infants and newborns (Caksen 2003 Laffargue 2011, Glatstein 2014, Rodríguez-González 2014).
There have been cases of gangrene when applied to the chest (Wani 2011).
Belladonna may be included in association with other “over the counter" medications of doubtful effectiveness or safety. Overall drug associations are not recommended.
Cautions when taking herbal teas:
1. Make sure it is obtained from a reliable source: reportedly, poisonings have occurred due to confusion after using another plant with toxic effects (Hsu 1995), some others contain heavy metals that may cause poisoning and others may cause food poisoning due to contamination with bacteria or fungi.
2. Do not take it excessively. "Natural" products are not always good in any amount: plants contain active substances from which are made many compounds of our traditional pharmacopoeia that can cause poisoning if consumed in exaggerated quantities or for long periods.
Alternatives
- Atropine (Very Low Risk)
- Atropine Ophtalmic Use (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Deadly Nightshade
Writings
- Atropa belladonna (Latin, botanical name)
Drug trade names
References
- Rodríguez-González M, Benavente Fernández I, Zafra Rodríguez P, Lechuga-Sancho AM, Lubián López S. Toxicity of remedies for infantile colic. Arch Dis Child. 2014Abstract
- Glatstein M, Danino D, Wolyniez I, Scolnik D. Seizures caused by ingestion of Atropa belladonna in a homeopathic medicine in a previously well infant: case report and review of the literature. Am J Ther. 2014Abstract
- Wani I, Bakshi I, Parray FQ, Malik AA, Wani RA, Shah M, Husasin I, Malik A, Wani S, Syed W. Breast gangrene. World J Emerg Surg. 2011Abstract
- Laffargue F, Oudot C, Constanty A, Bedu A, Ketterer-Martinon S. [Deadly nightshade (Atropa belladonna) intoxication in a 2-year-old child]. Arch Pediatr. 2011Abstract
- Lee MR. Solanaceae IV: Atropa belladonna, deadly nightshade. J R Coll Physicians Edinb. 2007Abstract
- Caksen H, Odabaş D, Akbayram S, Cesur Y, Arslan S, Uner A, Oner AF. Deadly nightshade (Atropa belladonna) intoxication: an analysis of 49 children. Hum Exp Toxicol. 2003Abstract
- Hsu CK, Leo P, Shastry D, Meggs W, Weisman R, Hoffman RS. Anticholinergic poisoning associated with herbal tea. Arch Intern Med. 1995Abstract