Is Boric Acid compatible with breastfeeding? Do we have alternatives for Boric Acid?

Boric Acid

June 9, 2018 (High Risk)

A chemical product used medically as a topical antiseptic (bacteria and fungi). It is also used as a disinfectant, insecticide and has other industrial uses. Given its toxic nature, its use as a food preservative has been abandoned. It is still used in the treatment of vaginal candidiasis when resistant to other treatment (Iavazzo 2011).

Since the last update we have not found published data on its excretion in breastmilk.

Absorption through intact skin is negligible (0.23%) (U.S. 2010, Wester 1998). Vaginal absorption is 6% (Prutting 1998).
Virtually everything absorbed via inhalation is eliminated in 24 hours and 96 hours if the absorption was through the digestive tract.

These periods of 24 and 96 hours can respectively be prudent periods of suspending breastfeeding in case the breastfeeding mother has been seriously intoxicated by inhalation or oral administration.

Alternatives

We do not have alternatives for Boric Acid.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Boracic Acid
  • Borax
  • Boron compounds
  • Hydrogen borate
  • Orthoboric Acid
  • Sassolite
  • Sodium Borate
  • Sodium Tetraborate

Writings

  • Βορικό οξύ (Greek)
  • Борная Кислота (Cyrillic)
  • ホウ酸 (Japanese)
  • H3 BO3 (Molecular formula)
  • S02AA03; S01AX07 (ATC Code/s)

References

  1. Iavazzo C, Gkegkes ID, Zarkada IM, Falagas ME. Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence. J Womens Health (Larchmt). 2011Abstract
  2. U.S. Agency for Toxic Substances and Disease Registry. Toxicological Profile for Boron. 2010 Full text (link to original source) Full text (in our servers)
  3. Prutting SM, Cerveny JD. Boric acid vaginal suppositories: a brief review. Infect Dis Obstet Gynecol. 1998Abstract Full text (link to original source) Full text (in our servers)
  4. Wester RC, Hui X, Maibach HI, Bell K, Schell MJ, Northington DJ, Strong P, Culver BD. In vivo percutaneous absorption of boron as boric acid, borax, and disodium octaborate tetrahydrate in humans: a summary. Biol Trace Elem Res. 1998Abstract
  5. Teshima D, Morishita K, Ueda Y, Futagami K, Higuchi S, Komoda T, Nanishi F, Taniyama T, Yoshitake J, Aoyama T. Clinical management of boric acid ingestion: pharmacokinetic assessment of efficacy of hemodialysis for treatment of acute boric acid poisoning. J Pharmacobiodyn. 1992Abstract
  6. Jansen JA, Andersen J, Schou JS. Boric acid single dose pharmacokinetics after intravenous administration to man. Arch Toxicol. 1984Abstract