It is a glycoprotein which is extracted from pineapple (Ananas comosus, Ananas sativos) and other fruits with a protease-like property (see specific info) and activity as proteolytic-like enzyme with the ability of protein digestion.
It is used in the food industry to softening the meat.
In medicine no proven utility has been shown. Effectiveness as an anti-inflammatory and digestive-enhancer is dubious. It has been topically used on local inflammations and burns.
It has been proposed for oral treatment of breast plethora (Murata 1965), yet there has been an only isolated and very old study which does not constitute an enough evidence to widely recommend it (Snowden 2007, ABM 2016). The few studies on oral protease utilization to alleviate breast plethora found out discordant results wiht low levels of evidence (ABM 2016, Mangesi 2016).
At latest update no published data were found on its excretion into breastmilk.
Because of a high molecular weight and a non-significant plasma level concentration (5 micrograms / L) the passage into breastmilk is seemingly unlikely.
See below the information of this related product:
- Proteases (Very Low Risk)
We do not have alternatives for Bromelains since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
- Pineapple Extract
- Plant Protease Concentrate
- Бромелаины (Cyrillic)
- ブロメライン (Japanese)
- C14H23CIN2O·H2O (Molecular formula)
- Mangesi L, Zakarija-Grkovic I. Treatments for breast engorgement during lactation. Cochrane Database Syst Rev. 2016Abstract
- Berens P, Brodribb W. ABM Clinical Protocol #20: Engorgement, Revised 2016. Breastfeed Med. 2016Abstract Full text (link to original source) Full text (in our servers)
- Academy of Breastfeeding Medicine. Protocolo Clínico de la ABM #20, revisión 2016: Congestión Mamaria. Breastfeed Medicine. 2016Abstract Full text (link to original source) Full text (in our servers)
- Academy of Breastfeeding Medicine. Protocolo Clínico de la ABM #20, revisión 2009: Congestión Mamaria. Breastfeed Med. 2009 Full text (in our servers)
- Snowden HM, Renfrew MJ, Woolridge MW. WITHDRAWN: Treatments for breast engorgement during lactation. Cochrane Database Syst Rev. 2007Abstract
- Castell JV, Friedrich G, Kuhn CS, Poppe GE. Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake. Am J Physiol. 1997Abstract
- Murata T, Hanzawa M, Nomura Y. The clinical effects of "protease complex" on postpartum breast engorgement (based on the double blind method). J Jpn Obstet Gynecol Soc. 1965Abstract