Is Cabergoline compatible with breastfeeding? Do we have alternatives for Cabergoline?

Cabergoline

January 10, 2015 (High Risk)

Ergot derivative alkaloid which is used to suppress lactation by inhibiting Prolactin release. Also used with levodopa for treatment of Prolactinoma and Parkinson disease.

No untoward effects have been reported in breastfed infants of mothers who were treated (or erroneously had received medication) and decided to resume breastfeeding.

Non-pharmacological methods used to suppress lactation are as effective as pharmacological ones.

Alternatives

We do not have alternatives for Cabergoline.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • カベルゴリン
  • كابارغولين
  • Καρβεγολίνη
  • Каберголин
  • 卡麦角林

Drug trade names

References

  1. Trimeloni L, Spencer J. Diagnosis and Management of Breast Milk Oversupply. J Am Board Fam Med. 2016Abstract Full text (link to original source) Full text (in our servers)
  2. PDR.net Cabergolina Drug Summary 2014 Full text (in our servers)
  3. Eglash A. Treatment of maternal hypergalactia. Breastfeed Med. 2014Abstract Full text (link to original source) Full text (in our servers)
  4. [No authors listed] Do not use drugs to prevent onset of lactation. Relieve the discomfort and wait. Prescrire Int. 2013Abstract
  5. Auriemma RS, Perone Y, Di Sarno A, Grasso LF, Guerra E, Gasperi M, Pivonello R, Colao A. Results of a single-center observational 10-year survey study on recurrence of hyperprolactinemia after pregnancy and lactation. J Clin Endocrinol Metab. 2013Abstract Full text (link to original source) Full text (in our servers)
  6. Shahzad H, Sheikh A, Sheikh L. Cabergoline therapy for macroprolactinoma during pregnancy: a case report. BMC Res Notes. 2012Abstract Full text (link to original source) Full text (in our servers)
  7. AEMPS Cabergolina Ficha Técnica 2011 Full text (link to original source) Full text (in our servers)
  8. Caballero-Gordo A, Lopez-Nazareno N, Calderay M, Caballero JL, Mancheño E, Sghedoni D. Oral cabergoline. Single-dose inhibition of puerperal lactation. J Reprod Med. 1991Abstract
  9. [No authors listed] Single dose cabergoline versus bromocriptine in inhibition of puerperal lactation: randomised, double blind, multicentre study. European Multicentre Study Group for Cabergoline in Lactation Inhibition. BMJ. 1991Abstract Full text (link to original source) Full text (in our servers)
  10. Melis GB, Mais V, Paoletti AM, Beneventi F, Gambacciani M, Fioretti P. Prevention of puerperal lactation by a single oral administration of the new prolactin-inhibiting drug, cabergoline. Obstet Gynecol. 1988Abstract