Cefatrizine

First-generation cephalosporins for oral administration. Actions and uses similar to those of cefalexin.

At latest update no published data on excretion into breast milk were found.

Their short half-life span make unlikely the milk passage of significant amounts into breast milk.

Most cephalosporins are excreted into milk in insignificant amounts from a therapeutic point of view without reported complications in infants.

Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant.

Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.

Alternatives

• Cefalexin (Very Low Risk)
• Cefalotin Sodium (Very Low Risk)