Cyproterone Acetate
Progestogen with antiandrogenic properties that is used for the treatment of conditions with hypersexuality, prostate carcinoma, transsexualism and, together with ethinyl estradiol, for hirsutism, acne and alopecia and hyperandrogenism in women.
It is excreted into breast milk in small quantities (Stoppelli 1980), but their anti-androgenic effects could be clinically significant for the infant when doses of 50 milligrams per day or higher are used.
The small amount (2 mg) contained in contraceptive tablets in which it is combined with ethinyl estradiol would represent a very low risk and would be compatible with breastfeeding.
Alternatives
We do not have alternatives for Cyproterone Acetate.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Writings
- Κυπροτερόνη οξική (Greek)
- Ципротерона Ацетат (Cyrillic)
- 酢酸シプロテロン (Japanese)
- C24H29ClO4 (Molecular formula)
Drug trade names
References
- Bayer. Diane. Product Monograph. 2014 Full text (in our servers)
- AEMPS. Ciproterona-Etinilestradiol. Ficha técnica. 2013 Full text (in our servers)
- AEMPS. Ciproterona. Ficha técnica. 2011 Full text (in our servers)
- AA Pharma. Cyproterone. Product Monograph. 2010 Full text (in our servers)
- Stoppelli I, Rainer E, Hümpel M. Transfer of cyproterone acetate to the milk of lactating women. Contraception. 1980Abstract