Is Dexibuprofen compatible with breastfeeding? Do we have alternatives for Dexibuprofen?

Dexibuprofen

September 28, 2014 (Very Low Risk)

On latest update no published data about breastfeeding were found. However, it is an enantiomer of Ibuprofen with similar pharmacokinetic properties. Ibuprofen has not been detected or only in very tiny amounts in the breast milk.

Because of a high plasma protein binding capacity, excretion into breast milk seems to be unlikely.

Alternatives

We do not have alternatives for Dexibuprofen since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • デキシブプロフェン
  • ديكسيبوبروفان
  • Дексибупрофен
  • 右布洛芬

Drug trade names

References

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  2. Hutchinson S, Marmura MJ, Calhoun A, Lucas S, Silberstein S, Peterlin BL. Use of common migraine treatments in breast-feeding women: a summary of recommendations. Headache. 2013Abstract Full text (link to original source) Full text (in our servers)
  3. Muralidharan S. Pharmacokinetic-pharmacodynamic model of newly developed dexibuprofen sustained release formulations. ISRN Pharm. 2012Abstract Full text (link to original source) Full text (in our servers)
  4. Yoon JS, Jeong DC, Oh JW, Lee KY, Lee HS, Koh YY, Kim JT, Kang JH, Lee JS. The effects and safety of dexibuprofen compared with ibuprofen in febrile children caused by upper respiratory tract infection. Br J Clin Pharmacol. 2008Abstract
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