Dibasic Sodium Phosphate
Phosphates are used as a laxative and to clean the bowel before medical examinations.
They base their action on the little or zero amount which is absorbed (Nice 2000), causing water to escape from the intestine and severe diarrhea.
Keep this in mind in order to drink as much as needed and avoid dehydration of the nursing mother who is already producing about 1 litre of liquid in the form of milk a day.
Since the last update, we have not found published data on its excretion in breast milk.
Both sodium and phosphate are normal components of the body and are found in breast milk at concentrations different to plasma (Allen 1991).
Temporary increases in plasma phosphate levels have been observed after the administration of sodium phosphate enema (Salix 2009, Ehrenpreis 2009). It is not known whether this may affect the concentration of phosphate in breast milk, but it is believed that the variation is minimal, temporary and does not have clinical repercussions in the infant.
Expert authors consider phosphate-based laxatives compatible with breastfeeding (Nice 2000).
Alternatives
We do not have alternatives for Dibasic Sodium Phosphate since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Writings
- νάτριο φωσφορικό (Greek)
- Ортофосфат Натрия Двузамещенный (Cyrillic)
- リン酸水素ナトリウム (Japanese)
- Phosphate disodique (French)
- Na2HPO4,xH2O (Molecular formula)
- Disodium hydrogen orthophosphate (Chemical name)
- A06AD17 (ATC Code/s)
- A06AG01 (ATC Code/s)
- B05XA09 (ATC Code/s)
Drug trade names
References
- Ehrenpreis ED. Increased serum phosphate levels and calcium fluxes are seen in smaller individuals after a single dose of sodium phosphate colon cleansing solution: a pharmacokinetic analysis. Aliment Pharmacol Ther. 2009Abstract
- Salix. Sodium phosphate mono & dibasic (Visicol). Drug Summary. 2009 Full text (in our servers)
- Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000Abstract
- Allen JC, Keller RP, Archer P, Neville MC. Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation. Am J Clin Nutr. 1991Abstract