Is Dienogest compatible with breastfeeding? Do we have alternatives for Dienogest?

Dienogest

July 15, 2017 (Very Low Risk)

Synthetic progesterone. Used for the treatment of endometriosis.
In association with estrogen it has been used as a birth-control medication (e.g. Estradiol + Dienogest)

A latest update no published data on excretion into breast milk were found. Progesterone and other related progestin drugs are excreted into breast milk in clinically non-significant amount, and, no problems have been observed in infants whose mothers were treated with this medication. Plasma levels of these infants were usually very low.

It has been occasionally observed an increase of prolactin with increased milk production, however, it would be advisable to start taking it until breastfeeding is well established (first 4 to 6 weeks postpartum).


See below the information of this related product:

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • دينوجاست (Arabic)
  • Диеногест (Cyrillic)
  • 地诺孕素 (Chinese)
  • ジエノゲスト (Japanese)
  • C20H25NO2 (Molecular formula)

References

  1. AEMPS. Dienogest. Ficha técnica. 2015 Full text (in our servers)
  2. Okada H, Nakajima T, Yoshimura T, Yasuda K, Kanzaki H. The inhibitory effect of dienogest, a synthetic steroid, on the growth of human endometrial stromal cells in vitro. Mol Hum Reprod. 2001Abstract