Is Flufenamic Acid compatible with breastfeeding? Do we have alternatives for Flufenamic Acid?

Flufenamic Acid

April 16, 2015 (Very Low Risk)

It is a non-steroidal anti-inflammatory topically used which is chemically related to Mefenamic acid. There are also formulations for oral use.

Excreted into breast milk in a clinically non-significant amount even after oral administration.

Because a low dose used and a poor absorption into the plasma of most dermatological preparations for topical use, its appearance in the breast milk is even less likely.

The American Academy of Pediatrics rated it as usual compatible with breastfeeding.

Alternatives

We do not have alternatives for Flufenamic Acid since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • CI-440; CN-27554; INF-1837; NSC-82699
  • حمض فلوفيناميك
  • Флуфенамовая Кислота
  • 氟芬那酸
  • フルフェナム酸

Drug trade names

References

  1. Köhler G, Tressel W, Dell HD, Doersing M, Fischer W, Kamp R, Langer M, Richter B, Wirzbach E. [Plasma- and tissue concentrations following intramuscular administration of etofenamat. Pharmacokinetics of etofenamat and flufenamic acid in plasma, synovium, and tissues of patients with chronic polyarthritis after administration of an oily solution of etofenamat]. Arzneimittelforschung. 1992Abstract
  2. Lentjes EG, van Ginneken CA. Pharmacokinetics of flufenamic acid in man. Int J Clin Pharmacol Ther Toxicol. 1987Abstract
  3. Buchanan RA, Eaton CJ, Koeff ST, Kinkel AW. The breast milk excretion on flufenamic acid. Curr Ther Res Clin Exp. 1969Abstract