Is Glucosamine compatible with breastfeeding? Do we have alternatives for Glucosamine?


June 4, 2016 (Very Low Risk)

Amino-monosaccharide that is a component of chitin, mucopolysaccharides and mucoproteins which is synthesized naturally in the body, found in cartilage, tendons and ligaments.
Very abundant in seafood.
It is used, without clearly scientific evidence of its efficacy, as an adjuvant treatment of osteoarthritis.
N-acetylglucosamine is a derivative of glucosamine which is found naturally in breast milk.

At latest update published were not found data on excretion in breast milk.

Its low bioavailability and rapid disappearance of the plasma stream makes it unlikely the pass into milk in significant amounts. It is a natural product with a very low toxic potential.


We do not have alternatives for Glucosamine since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.


  • Chitosamine
  • Glucosamine Hydrochloride
  • Glucosamine Sulfate Potassium Chloride
  • Glucosamine Sulfate Sodium Chloride
  • N-acetylglucosamine


  • غلوكوسامين (Arabic)
  • Глюкозамин (Cyrillic)
  • 氨基葡萄糖 (Chinese)
  • グルコサミン (Japanese)
  • C6H13NO5 (Molecular formula)


  1. The Royal Women’s Hospital Victoria Australia. Herbal and Traditional Medicines in Breasfeeding. Fact Sheet. 2013 Full text (link to original source) Full text (in our servers)
  2. AESAN. Informe del Comité Científico de la Agencia Española de Seguridad Alimentaria y Nutrición (AESAN) sobre condiciones de uso de determinadas sustancias distintas de vitaminas, minerales y plantas para ser empleadas en complementos alimenticios - 1. Revista del comité científico nº 17. 2012 Full text (in our servers)
  3. Amir LH, Pirotta MV, Raval M. Breastfeeding--evidence based guidelines for the use of medicines. Aust Fam Physician. 2011Abstract Full text (link to original source) Full text (in our servers)
  4. Rozendaal RM, Koes BW, van Osch GJ, Uitterlinden EJ, Garling EH, Willemsen SP, Ginai AZ, Verhaar JA, Weinans H, Bierma-Zeinstra SM. Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial. Ann Intern Med. 2008Abstract
  5. Setnikar I, Rovati LC. Absorption, distribution, metabolism and excretion of glucosamine sulfate. A review. Arzneimittelforschung. 2001Abstract
  6. Gudiel-Urbano M, Goñi I. [Human milk oligosaccharides. The rule in the health and development of the infants]. Arch Latinoam Nutr. 2001Abstract
  7. Miller JB, Bull S, Miller J, McVeagh P. The oligosaccharide composition of human milk: temporal and individual variations in monosaccharide components. J Pediatr Gastroenterol Nutr. 1994Abstract
  8. Setnikar I, Palumbo R, Canali S, Zanolo G. Pharmacokinetics of glucosamine in man. Arzneimittelforschung. 1993Abstract