Ibuprofen
A non-steroidal anti-inflammatory indicated in the treatment of fever, pains, rheumatoid arthritis and other rheumatic complaints.
Oral, intravenous and topical administration (cutaneous or vaginal), every 6 to 8 hours.
Its pharmacokinetic data (high percentage of protein binding, acidic character and short half-life) explain the tiny or zero transfer of milk observed (Rigourd 2014, Walter 1997, Townsend 1984, Albert 1984, Weibert 1982).
No problems have been observed in infants whose mothers were taking it (Walter 1997, Ito 1993, Weibert 1982).
A medication commonly used in pediatrics. Its use is authorized from 6 months of age. The dose that an infant can receive through breastmilk is hundreds of times inferior to the therapeutic dose given to an infant (Rigourd 2014, Walter 1997).
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).
List of essential WHO medications: compatible with breastfeeding (WHO/UNICEF, 2002).
Expert authors and medical associations consider it compatible with breastfeeding (Reece 2017, Bordini 2016, Noviani 2016, Davanzo 2014, Sachs 2013, Worthington 2013, Hutchinson 2013, Rowe 2013, Amir 2011, Chen 2010, Risser 2009, Østensen 2007, Spigset 2000 , Janssen 200, Nice 2000, Mitchell 1999, Goldsmith 1989, Needs 1985).
It is regarded as the analgesic of choice for breastfeeding mothers (Worthington 2013, Østensen 2007, Nice 2000).
Alternatives
We do not have alternatives for Ibuprofen since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Ibuprofen Arginine
- Ibuprofen Lysine
Writings
- Ιβουπροφαίνη (Greek)
- إيبوبروفان (Arabic)
- Ибупрофен (Cyrillic)
- 布洛芬 (Chinese)
- イブプロフェン (Japanese)
- Ibuprofène (French)
- C13 H18 O2 (Molecular formula)
- 2-(4-Isobutylphenyl)propionic acid (Chemical name)
- C01EB16; G02CC01; M01AE01; M02AA13; R02AX02 (ATC Code/s)
Drug trade names
- Aches-N-Pain™
- ACT-3™
- Actiprofen™
- Actron Plus™ (Mexico)
- Actron™
- Acuilfem™
- Advil (雅维)™
- Advil™
- Afebril™
- Aflusil™
- Ainex™
- Aktren™
- Aldofen™
- Aldospray (Альдоспрей)™
- Algiasdin™
- Algidol™ (Mexico)
- Algifene™ (France)
- Algiflex™
- Algioprofen™
- Algofen™
- Algoflex™
- Algofren™
- Algy-Flanderil™
- Alindrin™
- Altior™
- Ambufen™
- An Rui Ke (安瑞克)™
- Anadar™
- Anadin Ultra™
- Anadvil™
- Anbifen™
- Antalgil™ (Italy)
- Antarene™
- Apain™
- Aprofen™
- Arfen™
- Arthrofen™
- Artofen™
- Artril™
- ArtroCam (АртроКам)™
- Avallone™
- Babefen Sus™
- Bang Qi (邦奇)™
- Bediatil™
- Bei De Fen (倍得芬)™
- Bei Fen (倍芬)™
- Bestafen™
- Betagesic™
- Betaprofen™
- Biatain-Ibu™
- Bifen™
- Bistryl™
- Bofen (Бофен)™
- Bonifen (Бонифен)™
- Borafen™
- Borakid™
- Brufen (Бруфен)™
- Brufen™
- Brugesic™
- Bruprin™
- Brusil™
- Bufen (Ибуфен)™
- Bufigen™ (Ireland)
- Bumed™
- Bupogesic™
- Buprifen™
- Buprodol™
- Burana (Бурана)™
- Burana™
- Buscofen™
- Butafen™
- Butidiona™
- Butilene™
- Caffetin Lady (Каффетин Леди™
- Caldolor™
- Calmafher™
- Calmine™
- Calprofen™
- Carone™
- Causalon Ibu™
- Cefen™
- Cibalgina Due Fast™
- Cipgesic™
- Citalgan™
- Colfene™ (Venezuela)
- Contraneural™
- Copiron™
- Cramp End™
- Cuprofen™
- Dadicil™
- Dalsy™
- Days™
- Deucodol™
- Di Er Nuo (迪尔诺)™
- Dibufen™
- Diltix™
- Dipofen™
- Diprodol™
- Dismenol Neu™
- Dismenol N™
- Dolbufen™
- Dolex™ (Philippines)
- Dolgit (Долгит)™
- Dolgit™
- Dolibu™
- Dolo Sanol™
- Dolo-Dismenol™
- Dolo-Puren™
- Dolocox™
- Dolocyl™
- Dolodoc™
- Dolofort™
- Dologesic™
- Dolorac™
- Dolorsyn™
- Dolorub™
- Dolprin™
- Dolprofen™
- Doltaque™
- Dolval™
- Dolver™
- Doraplax™
- Doretrim™
- Dorival™
- Dristan triple acción™
- Druisel™
- Duafen™
- Duexis™
- Duran™
- Dynafed IB™
- Ebufac™
- Ecoprofen™
- Efficover (芬克)™
- Emflam™
- Epsilon™
- Ergix douleur et fievre™
- Espididol™
- Espidifen™
- EtIbufen (布洛芬缓释)™
- Eudorlin Extra™
- Eudorlin Migrane™
- Eufenil™
- Excedrin IB™
- Expanfen™
- Extrapan™
- Fabogesic™
- Factopan™
- Faspic (Фаспик)™
- Faspic™
- Febratic™
- Femapirin™
- Femicaps™
- Feminalin™
- Femmex Plus™
- Fen Su (芬苏)™
- Fenapaed™
- Fenbid (芬必得)™
- Fenbid™
- Fennikang (芬尼康)™
- Fenopine™
- Fenpaed™
- Feverfen™
- Flexafen™
- Flexina™
- Fontol™
- Fortapal™
- Frenador™
- Fu Er Da (抚尔达)™
- Fu Er Shuan (福尔栓)™
- G-Fen™
- Galprofen™
- Gelofeno™
- Gelufene™
- Genpril™
- Gobrosan™
- Greatofen™
- Grefen™
- Gyno-Neuralgin™
- Haltran™
- Heidi™
- Hemagene Tailleur™
- Huanshifen (缓士芬)™
- Huma-Profen™
- Ib-Profeno™
- Ibalgin (Ибалгин)™
- Ibifon™
- Iboflam™
- Ibosure™
- Ibrofen™
- Ibrufhalal™
- Ibu Benuron™
- Ibu Evanol™
- Ibu-4™
- Ibu-6™
- Ibu-Attritin™
- Ibu-Lady™
- Ibu-Novalgina™
- Ibu-Slow™
- Ibu-Tab™
- Ibubeta™
- Ibubex™
- Ibucaps™
- Ibucare™
- Ibucler™
- Ibudolor™
- Ibudol™
- Ibufac™
- Ibufem™
- Ibufen (Ибуфен)™
- Ibufenac™
- Ibufen™
- Ibufix™
- Ibuflam™
- Ibuflex™
- Ibufran™
- Ibugan™
- Ibugel™
- Ibugesic™
- Ibulan™
- Ibuleve™
- Ibulgan™
- Ibulos™
- Ibumac™
- Ibumar™
- Ibumax™
- Ibumed™
- Ibumerck™
- Ibumetin™
- Ibumultin™
- Ibupax™
- Ibupen™
- Ibupirac™
- Ibupiretas™
- Ibupril™
- Ibuprin™
- Ibuprofan™
- Ibuprom (Ибупром)™
- Ibuprox™
- Iburem™
- Iburen™
- Ibureumin™
- Ibusal™
- Ibusifar™
- Ibusi™
- Ibusumal™
- Ibutab™
- Ibutan™
- Ibutard (Ибутард)™
- Ibutenk™
- Ibu™
- Ibutop™
- Ibuxin™
- Ibuzidine™
- Imet (Имет)™
- Inpained™
- Intralgis™
- Inza™ (South Africa)
- Ipren™
- Iproben™
- Iprogel™
- Ipson™
- Irfen (Ирфен)™
- Irfen™
- Isdibudol™
- Isdol™
- Jenaprofen™
- Jie Le (捷乐)™
- Jihao (吉浩)™
- Jiubaofen (久保芬)™
- Junifen™
- Kesan™
- Kin™
- Kontagripp™
- Kratalgin™
- Librofem™
- Lombalgina™
- Lumbax™
- Malafene™
- Mandafen™
- Manorfen™
- Matrix™
- Maxifen™
- Max™
- Maydol™
- Medipren™
- Mejorultra™
- Melabon™
- Melfen™
- Menadol™
- Mensoton™
- Mestral™
- Midol Cramp & Body Aches™
- Mig (Миг)™
- Migrafen™
- Moment™
- Motrin™
- Narfen™
- Natiken™
- Neobrufen™
- NeoProfen™
- Neutropain™
- Niofen™ (Chile)
- Nodolfen™
- Norflam T™
- Nortafen (Нортафен)™
- Novaprin™
- Novigan™
- Novo Geniol™
- Novo-Profen™
- Nuprilan™
- Nuprin™
- Nureflex™
- Nurofen (Нурофен)™
- Nurofentabs™
- Nurofen™
- Nuroflash™
- Oberdol™
- Obifen™
- Oltyl™
- Optalidon™ (Germany)
- Optifen™
- Opturem™
- Orbifen™
- Ostofen™
- Oxibut™
- Ozonol™
- P-Fen™
- Pabiprofen™
- Pacifene™
- Paidofebril™
- Pakurat™
- Panafen™
- Parartrin™
- Parsal™
- Pedea (Педеа)™
- Pedea™
- Pediaprofen™
- Pedibu™
- Perofen™
- Pfeil™
- Phor Pain™
- Phorpain™
- Pippen™
- Pirexin™
- Pironal™
- Ponstil Mujer™
- Ponstinetas™
- Ponstin™
- Proartinal™
- Probufen™
- Probuxil™
- Profeno™
- Profen™
- Profinal™
- ProFLEX™
- Pyriped™
- Qin Fu (琴福)™
- Qing Fen (清芬)™
- Quadrax™
- Rafen™
- Ranfen™
- Realdrax™
- Relcofen™
- Rheumanox™
- Ribufen™
- Rimafen™
- Roco™
- Rufen™
- Rumasian™
- Rumatifen™
- Rupan™
- Saetil™
- Sai Ke (赛可)™
- Saleto-200™
- Salivia™
- Schmerz-Dolgit™
- Schufen™
- Sindol™
- Siprofen™
- Skelan IB™
- Solfen™
- Solpaflex (Солпафлекс)™
- Solpaflex™
- Solufen™
- Solvium™
- Spalt™
- Spedifen (司百得)™
- Spedifen™
- Spifen™
- Sporfen™
- Tabalon™
- Tai Bao (泰宝)™
- Tedifebrin™
- Teprix™
- Tian Qian (恬倩)™
- Tifen™
- Tofen™
- Trauma-Dolgit™
- Trendar™
- Tri-Profen™
- Trifene™
- Trofen™
- Tuen (托恩)™
- Uniprofen™
- Upfen™
- Urem™
- Urgo™
- Xin Di Fen (欣荻芬)™
- Xin Wei (欣卫)™
- Yi Fen Ning (怡芬宁)™
- Zafen™
- Zefen (泽芬)™
- АРОФЕН ДЛЯ ДІТЕЙ
- АФФИДА МАКС
- БОФЕН
- БРУФЕН®
- БРУФЕН® ФОРТЕ
- ГІНЕНОРМ
- ГОФЕН 200
- ГОФЕН 400
- ДОЛГІТ® ГЕЛЬ
- ДОЛГІТ® КРЕМ
- ЄВРОФАСТ
- ІБУНОРМ
- ІБУНОРМ БЕБІ
- ІБУПРОМ
- ІБУПРОМ ДЛЯ ДІТЕЙ
- ІБУПРОМ ДЛЯ ДІТЕЙ ФОРТЕ
- ІБУПРОМ ЕКСТРА
- ІБУПРОМ МАКС
- ІБУПРОМ СПРИНТ КАПС
- ІБУПРОФЕН
- ІБУПРОФЕН 500 мг
- ІБУПРОФЕН-ДАРНИЦЯ
- ІБУТАРД 300
- ІБУТЕКС
- ІБУФЕН® ДЛЯ ДІТЕЙ МАЛИНА
- ІБУФЕН® ДЛЯ ДІТЕЙ ПОЛУНИЦЯ
- ІБУФЕН® ФОРТЕ
- ІБУФЕН® ЮНІОР
- ІМЕТ®
- ІМЕТ® ДЛЯ ДІТЕЙ 2 %
- ІМЕТ® ДЛЯ ДІТЕЙ 4 %
- КАФФЕТІН® ЛЕДІ
- МІНІДОЛ
- НЕОФЕН БЕЛУПО
- НЕОФЕН БЕЛУПО ПЛЮС
- НЕОФЕН БЕЛУПО ФОРТЕ
- НУРОФЄН®
- НУРОФЄН® ДЛЯ ДІТЕЙ
- НУРОФЄН® ДЛЯ ДІТЕЙ ФОРТЕ
- НУРОФЄН® ЕКСПРЕС
- НУРОФЄН® ЕКСПРЕС РОЗЧИННИЙ
- НУРОФЄН® ЕКСПРЕС УЛЬТРАКАП
- НУРОФЄН® ЕКСПРЕС ФОРТЕ
- НУРОФЄН® ЛЕДІ
- НУРОФЄН® ФОРТЕ
- ОРАФЕН
- ФАСПІК
References
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