Lactulose
Disaccharide (galactose and fructose) which is barely absorbed by the small intestine and reaches the large intestine (colon) where it exerts its action as an osmotic laxative drug. A small amount that is absorbed is excreted unmodified in the urine.
At latest update were not found published data on excretion into breast milk. However, because it does not reach the mother's plasma, any concentration in the milk is not expected.
Medication with authorized indication in infants.
Alternatives
We do not have alternatives for Lactulose since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- ラクツロース
- لاكتولوز
- Лактулоза
- 乳果糖
Drug trade names
References
- Gharehbaghi K, Gharehbaghi DR, Wierrani F, Sliutz G. [Treatment of Chronic Functional Constipation during Pregnancy and Lactation]. Z Geburtshilfe Neonatol. 2016Abstract
- Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006Abstract Full text (link to original source) Full text (in our servers)
- Müller M, Jaquenoud E. [Treatment of constipation in pregnant women. A multicenter study in a gynecological practice]. Schweiz Med Wochenschr. 1995Abstract