Lansoprazole
At latest update, relevant information on excretion into breast milk was not found.
Due to a high serum-protein-binding capacity, excretion of Lansoprazole into breast milk is non-significant.
Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of Lansoprazole that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food.
Both Omeprazole and Pantoprazole pertain to the same chemical group with similar pharmacokinetics that are excreted in non-significant amount into the breast milk.
Medication that has been used for treatment of newborn and premature infants.
Hyperprolactinemia and galactorrhea have been reported by the use of such medication, though some authors have failed to show the same findings.
Alternatives
- Famotidine (Very Low Risk)
- Omeprazole (Very Low Risk)
- Pantoprazole (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- ランソプラゾール
- لانسوبرازول
- Λανσοπραζόλη
- Ланзопразол
- 兰索拉唑
Drug trade names
- Agopton™
- Apradil™
- Bamalite™
- Elcodil™
- Epicur (Эпикур)™
- Estomil™
- Fudermex™
- Gastride™
- Helicol (Геликол)™
- Ilsatec™
- Juniorlanzol™
- Lancid (Ланцид)™
- Lancid™
- Lanciprol™
- Langastrol™
- Lansobene™
- Lansofed (Лансофед)™
- Lansohexal™
- Lansoptol (Ланзоптол)™
- Lanso™
- Lansox™
- Lanzoacid™
- Lanzogastro™
- Lanzole™
- Lanzol™
- Lanzopral™
- Lanzopran™
- Lanzor™
- Lanzo™
- Lapol™
- Laprazol™
- Mesactol™
- Monolitum™
- Ogasto™
- Ogastro™
- Opiren™
- Palatrin™
- Pampe™
- Prevacid (普托平)™
- Prevacid™
- Pro Ulco™
- Protoner™
- Safemar™
- Serax™ (Mexico)
- Ulcertec™
- Uldapril™
- Ulpax™
- Unimet™
- Unival™ (Chile)
- Zoletad™
- Zomel™ (Ireland)
- Zopral™
- Zoton™
- ЛАНЗА
- ЛАНЗОПТОЛ
- ЛАНСОПРАЗОЛУ ПЕЛЕТИ
- ЛАНСОПРОЛ®
- ЛАНЦЕРОЛ®
References
- Comité de Medicamentos de la Asociación Española de Pediatría. Lansoprazol Pediamecum 2014 Full text (link to original source) Full text (in our servers)
- Jabbar A, Khan R, Farrukh SN. Hyperprolactinaemia induced by proton pump inhibitor. J Pak Med Assoc. 2010Abstract
- Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006Abstract Full text (link to original source) Full text (in our servers)
- Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005Abstract Full text (in our servers)
- Izquierdo Prieto OM, Moreno Alía E, Rosillo González A. [Galactorrhea induced by lansoprazole]. Aten Primaria. 2004Abstract
- Dammann HG, von zur Mühlen A, Balks HJ, Damaschke A, Steinhoff J, Hennig U, Schwarz JA, Fuchs W. The effects of lansoprazole, 30 or 60 mg daily, on intragastric pH and on endocrine function in healthy volunteers. Aliment Pharmacol Ther. 1993Abstract