Lincomycin

A Lincosamide type antibacterial drug which is structurally similar to clindamycin.

As clindamycin, it is excreted in breast milk in clinically non-significant amount with no problems being reported in infants whose mothers were treated with it.

Its low oral bioavailability that further decreases with simultaneous ingestion of food, hinders the drug passage to the infant plasma from ingested mother’s milk , except in preterm babies and immediate neonatal period, in which they may occur an increased intestinal permeability.

Among infants whose mothers are treated with antibiotics, an alteration of the intestinal flora may appear. In case of infant's fever, the possibility of false negative results of bacterial cultures should be taken into account.

Alternatives

We do not have alternatives for Lincomycin since it is relatively safe.