Lyme Disease Vaccine
A vaccine made of recombinant outer surface proteins from Borrelia burgdorferi (CDC1999).
Since the last update, we have not found any published data on its excretion in breast milk.
Its very high molecular weight makes its transfer to milk in significant quantities very unlikely.
Its low oral bioavailability would hinder its transfer to the infant’s plasma from ingested breast milk because, due to its protein nature, it degrades in the gastrointestinal tract, and is not absorbed.
This vaccine was withdrawn from sale in 2002, after only a few years of availability (FDA 2002) for reasons unrelated to its effectiveness (Kaaijk 2016, Aronowitz 2012).
Vaccines are compatible with breastfeeding, both those that are live attenuated microorganisms, as well as those that are dead, inactivated or those formed by parts of or toxoids of the same (Sachs 2013, CDC 2011).
With the exception of rubella, smallpox and yellow fever, live virus vaccines are not excreted in breast milk and do not cause problems in infants, except for yellow fever in children under 6 months (Sachs 2013, CDC 2011).
Breastfeeding can improve the antibody response of vaccines (CDC 2011).
Women who breastfeed can and should be protected with the recommended vaccines like other adults.
See below the information of this related product:
- Maternal Lyme disease (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- OspA lipoprotein
Writings
- C1198H2012N322O422S2 (Molecular formula)
References
- Kaaijk P, Luytjes W. Vaccination against Lyme disease: Are we ready for it? Hum Vaccin Immunother. 2016Abstract Full text (link to original source)
- Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013Abstract Full text (link to original source) Full text (in our servers)
- Aronowitz RA. The rise and fall of the lyme disease vaccines: a cautionary tale for risk interventions in American medicine and public health. Milbank Q. 2012Abstract Full text (link to original source)
- National Center for Immunization and Respiratory Diseases. General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011Abstract Full text (in our servers)
- [No authors listed] Manufacturer discontinues only Lyme disease vaccine. FDA Consum. 2002Abstract Full text (link to original source)
- Centers for Disease Control and Prevention (CDC).. Availability of Lyme disease vaccine. MMWR Morb Mortal Wkly Rep. 1999Abstract Full text (link to original source)