Mivacurium
It is a non-depolarizing muscle relaxant drug with a peripheral action that is used as premedication for endotracheal intubation, general anesthesia and mechanical ventilation.
At latest update, no relevant published data concerning excretion into breast milk were found.
A high molecular weight may decrease excretion into breast milk as well as a rapid elimination time.
In addition, a low oral bioavailability makes unlikely a pass from ingested mother's milk onto the infant's plasma.
Mivacurio should not prevent a mother from breast feeding her baby shortly after recovering from an anesthesia if she is in good condition.
Alternatives
We do not have alternatives for Mivacurium since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Mivacurium Chloride
- كلوريد ميفاكوريوم
- μιβακούριο χλωριούχο
- Мивакурия Хлорид
- 塩化ミバクリウム
- 米库氯铵
Drug trade names
References
- Dalal PG, Bosak J, Berlin C. Safety of the breast-feeding infant after maternal anesthesia. Paediatr Anaesth. 2014Abstract
- Atherton DP, Hunter JM. Clinical pharmacokinetics of the newer neuromuscular blocking drugs. Clin Pharmacokinet. 1999Abstract
- Ferriols Lisart R,Ferriols Lisart F. Farmacología clínica y usos terapéuticos del Mivacurio. Farm Hosp. 1997 Full text (in our servers)
- Spigset O. Anaesthetic agents and excretion in breast milk. Acta Anaesthesiol Scand. 1994Abstract
- Frampton JE, McTavish D. Mivacurium. A review of its pharmacology and therapeutic potential in general anaesthesia. Drugs. 1993Abstract