Is Nicardipine Hydrochloride compatible with breastfeeding? Do we have alternatives for Nicardipine Hydrochloride?

Nicardipine Hydrochloride

June 4, 2016 (Very Low Risk)

Its excretion into breast milk is almost null (undetectable in 82% of cases) or in clinically non-significant amount possibly due to its high protein-binding capacity in the plasma.

Alternatives

We do not have alternatives for Nicardipine Hydrochloride since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • νικαρδιπίνη υδροχλωρική (Greek)
  • Никардипина Гидрохлорид (Cyrillic)
  • ニカルジピン塩酸塩 (Japanese)
  • C26H29N3O6,HCl (Molecular formula)

Drug trade names

References

  1. Serrano Aguayo P, García de Quirós Muñoz JM, Bretón Lesmes I, Cózar León MV. Tratamiento de enfermedades endocrinológicas durante la lactancia. [Endocrinologic diseases management during breastfeeding.] Med Clin (Barc). 2015Abstract
  2. Matsumura H, Takagi K, Seki H, Ono Y, Ichinose S, Masuko H, Fukatsu M, Miyashita A, Mera A. Placental transfer of intravenous nicardipine and disposition into breast milk during the control of hypertension in women with pre-eclampsia. Hypertens Pregnancy. 2014Abstract
  3. Bartels PA, Hanff LM, Mathot RA, Steegers EA, Vulto AG, Visser W. Nicardipine in pre-eclamptic patients: placental transfer and disposition in breast milk. BJOG. 2007Abstract Full text (link to original source) Full text (in our servers)