Is Oxytocin compatible with breastfeeding? Do we have alternatives for Oxytocin?

Oxytocin

October 28, 2014 (Very Low Risk)

It stimulates the ejection reflex by intranasal dose of 12 units (6 in every nostril) before nursing or pumping. Useful at the beginning of lactation, but not recommended for longer than 2-3 weeks as it may be a source of dependency on the mother.

Alternatives

We do not have alternatives for Oxytocin since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013Abstract Full text (link to original source) Full text (in our servers)
  2. Forinash AB, Yancey AM, Barnes KN, Myles TD. The use of galactogogues in the breastfeeding mother. Ann Pharmacother. 2012Abstract
  3. Mannion C, Mansell D. Breastfeeding self-efficacy and the use of prescription medication: a pilot study. Obstet Gynecol Int. 2012Abstract Full text (link to original source) Full text (in our servers)
  4. Muresan M. Successful relactation--a case history. Breastfeed Med. 2011Abstract
  5. Zuppa AA, Sindico P, Orchi C, Carducci C, Cardiello V, Romagnoli C. Safety and efficacy of galactogogues: substances that induce, maintain and increase breast milk production. J Pharm Pharm Sci. 2010Abstract Full text (link to original source) Full text (in our servers)
  6. Guerra GV, Cecatti JG, Souza JP, Faúndes A, Morais SS, Gülmezoglu AM, Parpinelli MA, Passini R Jr, Carroli G; World Health Organisation 2005 Global Survey on Maternal and Perinatal Health Research Group. Factors and outcomes associated with the induction of labour in Latin America. BJOG. 2009Abstract Full text (link to original source) Full text (in our servers)
  7. Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact. 2002Abstract
  8. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  9. Ylikorkala O, Kauppila A, Kivinen S, Viinikka L. Treatment of inadequate lactation with oral sulpiride and buccal oxytocin. Obstet Gynecol. 1984Abstract