Is Paraminosalicylic Acid compatible with breastfeeding? Do we have alternatives for Paraminosalicylic Acid?

Paraminosalicylic Acid

July 5, 2014 (Very Low Risk)

Drug related to same group of 5-aminosalicylic Acid

It is excreted in tiny amounts into breast milk with no reported cases of harm effects except a case of mild gastroenteritis.

Alternatives

We do not have alternatives for Paraminosalicylic Acid since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • 4-Aminosalicylic Acid
  • PAS

Drug trade names

References

  1. Arbex MA, Varella Mde C, Siqueira HR, Mello FA. Antituberculosis drugs: drug interactions, adverse effects, and use in special situations. Part 2: second line drugs. J Bras Pneumol. 2010Abstract Full text (link to original source) Full text (in our servers)
  2. Drobac PC, del Castillo H, Sweetland A, Anca G, Joseph JK, Furin J, Shin S. Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents. Clin Infect Dis. 2005Abstract Full text (link to original source) Full text (in our servers)
  3. Silverman DA, Ford J, Shaw I, Probert CS. Is mesalazine really safe for use in breastfeeding mothers? Gut. 2005Abstract Full text (link to original source) Full text (in our servers)
  4. Jenss H, Weber P, Hartmann F. 5-Aminosalicylic acid and its metabolite in breast milk during lactation. Am J Gastroenterol. 1990Abstract
  5. Nelis GF. Diarrhoea due to 5-aminosalicylic acid in breast milk. Lancet. 1989Abstract
  6. Holdiness MR. Antituberculosis drugs and breast-feeding. Arch Intern Med. 1984Abstract Full text (link to original source) Full text (in our servers)