Racecadotril
An anti-enkephalin that decreases intestinal secretion.
Since the latest update, we have not found published data on its excretion in breast milk.
Its high percentage of protein binding makes it unlikely it will transfer to milk in significant quantities.
Possible side effects are not serious or frequent.
Its use is authorized in infants from 3 months of age (Pediamecum 2015)
Its indiscriminate use in treating gastroenteritis is not justified. Most cases of gastroenteritis do not require medication: good hydration is sufficient, even more so in the case of a breastfeeding mother.
Alternatives
- Oral rehydration salt formulations (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Acetorphan
Writings
- راسيكادوتريل (Arabic)
- Рацекадотрил (Cyrillic)
- 消旋卡多曲 (Chinese)
- ラセカドトリル (Japanese)
- Racécadotril (French)
- C21H23NO4S (Molecular formula)
- (±)-N-{2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl}glycine phenylmethyl ester; N-[(R,S)-3-acetylthio-2-benzylpropanoyl]glycine benzyl ester; (±)-N-[α-(Mercaptomethyl)hydrocinnamoyl]glycine benzyl ester acetate (Chemical name)
- A07XA04 (ATC Code/s)
Drug trade names
References
- AEMPS. Racecadotrilo. Ficha técnica. 2017 Full text (in our servers)
- Comité de Medicamentos de la Asociación Española de Pediatría. Racecadotrilo. Pediamécum. 2015 Full text (in our servers)
- MRI Index. Racecadotril. Drug Summary. 2007 Full text (in our servers)