Ruscogenin
A sapogenin obtained from the roots of the ruscus aculeatus shrub. Used topically to treat hemorrhoids and varicose veins.
Since the last update we have not found published data on its excretion in breast milk.
The small dose and low plasma absorption of most topical dermatological preparations make it unlikely that a significant amount will transfer into breastmilk.
Some cases of contact dermatitis have been detected after the topical use of antihemorrhoidal ointments that included ruscogenin in their composition (Gonzalo-Garijo MA et al 2009, Cordoba et al 2009, Ramírez-Hernández M. et al 2006).
For the sake of prudence and to avoid contact with the baby’s skin, it is recommended that you wash your hands well after applying the cream.
See below the information of this related product:
- Butcher´s Broom (Very Low Risk)
Alternatives
We do not have alternatives for Ruscogenin since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Espyrostendiol
Writings
- Ρουσκογενίνη (Greek)
- Рускогенин (Cyrillic)
- ルスコゲニン (Japanese)
- Ruscogénine (French)
- C27H42O4 (Molecular formula)
- (25R)-Spirost-5-ene-1β,3β-diol (Chemical name)
Drug trade names
References
- Córdoba S, Martínez-Morán C, Hernández-Nuñez A, Borbujo J. Contact dermatitis from an anti-haemorroidal cream containing ruscogenin. Eur J Dermatol. 2009Abstract
- Gonzalo-Garijo MA, Pérez-Calderón R, Chaves-Alvarez A, Pérez-Rangel I, Rodríguez-Nevado I. Compound allergy to an antihemorrhoidal ointment demonstrated by the repeated open application test. J Investig Allergol Clin Immunol. 2009Abstract
- Ramírez-Hernández M, García-Sellés J, Mérida-Fernández C, Martínez-Escribano JA. Allergic contact dermatitis to ruscogenins. Contact Dermatitis. 2006Abstract
- [No authors listed] Ruscus aculeatus (butcher's broom). Monograph. Altern Med Rev. 2001Abstract Full text (link to original source) Full text (in our servers)