Is Saccharomyces boulardii compatible with breastfeeding? Do we have alternatives for Saccharomyces boulardii?

Saccharomyces boulardii

July 31, 2017 (Very Low Risk)

A yeast strain isolated from various tropical fruits. Related to saccharomyces cerevisiae or brewer's yeast. Unicellular fungus which produces lactic acid used as a probiotic to regenerate the intestinal flora in case of infectious diarrhea or diarrhea associated with taking antibiotics.

There is controversy about its effectiveness (Hayes 2016, Ehrhardt 2016, MedlinePlus 2015, Szajewska 2015) and although it is considered a safe product in immunocompetent people, there have been cases of widespread infection by the fungus itself in the absence of immune deficiency (Martin 2017) .

Since the last update we have not found published data on its excretion in breast milk but due to its lack of intestinal absorption it is considered safe during breastfeeding.


See below the information of these related products:

Alternatives

We do not have alternatives for Saccharomyces boulardii since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. Martin IW, Tonner R, Trivedi J, Miller H, Lee R, Liang X, Rotello L, Isenbergh E, Anderson J, Perl T, Zhang SX. Saccharomyces boulardii probiotic-associated fungemia: questioning the safety of this preventive probiotic's use. Diagn Microbiol Infect Dis. 2017Abstract
  2. Ehrhardt S, Guo N, Hinz R, Schoppen S, May J, Reiser M, Schroeder MP, Schmiedel S, Keuchel M, Reisinger EC, Langeheinecke A, de Weerth A, Schuchmann M, Schaberg T, Ligges S, Eveslage M, Hagen RM, Burchard GD, Lohse AW. Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea: A Randomized, Double-Masked, Placebo-Controlled Trial. Open Forum Infect Dis. 2016Abstract
  3. Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016Abstract
  4. Szajewska H, Kołodziej M. Systematic review with meta-analysis: Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2015Abstract
  5. MedlinePlus. Saccharomyces boulardii. Información de salud para usted. 2015 Full text (link to original source) Full text (in our servers)
  6. MedlinePlus Saccharomyces boulardii. Trusted Health Information for You. 2015 Full text (link to original source) Full text (in our servers)