Is Salicylic Acid compatible with breastfeeding? Do we have alternatives for Salicylic Acid?

Salicylic Acid

November 7, 2015 (Very Low Risk)

It is topically used as a keratolytic, antiseptic, antifungal, dermatological and stomatological agent.

At last update no published data on excretion into breast milk were found .

Systemic absorption (distribution into the body) depends on the concentration of the product used and the duration of application. Absorption may reach 10 to 25% of the total amount applied on the skin. It is recommended not to use during lactation in large areas of skin or for prolonged periods.

Available data on the elimination of Acetylsalicylic acid (Aspirin-ASA) in breast milk indicates it is clinically insignificant.
No cases have been reported on Reye's syndrome by ASA through the breast milk which is considered very unlikely to occur with isolated and/or small doses used as antithrombotic treatments and anti-abortion measures, even less after application on the skin or topically in the mouth.

Do not apply on the breast to prevent ingestion by the infant. If necessary, apply it after the feed and wipe it off thoroughly with water before the next feed.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • σαλικυλικό οξύ (Greek)
  • Салициловая Кислота (Cyrillic)
  • サリチル酸 (Japanese)
  • C7H6O3 (Molecular formula)

References

  1. Murase J. Safe Skin Care During Pregnancy and Breastfeeding. Fact Sheet. For the media. American Academy of Dermatology. 2015 Full text (link to original source) Full text (in our servers)
  2. Madan RK, Levitt J. A review of toxicity from topical salicylic acid preparations. J Am Acad Dermatol. 2014Abstract Full text (link to original source) Full text (in our servers)
  3. Kong YL, Tey HL. Treatment of acne vulgaris during pregnancy and lactation. Drugs. 2013Abstract
  4. Fung W, Orak D, Re TA, Haughey DB. Relative bioavailability of salicylic acid following dermal application of a 30% salicylic acid skin peel preparation. J Pharm Sci. 2008Abstract
  5. Unsworth J, d'Assis-Fonseca A, Beswick DT, Blake DR. Serum salicylate levels in a breast fed infant. Ann Rheum Dis. 1987Abstract Full text (link to original source) Full text (in our servers)