Is Secnidazole compatible with breastfeeding? Do we have alternatives for Secnidazole?

Secnidazole

July 5, 2015 (Very Low Risk)

On last update relevant published data concerning breastfeeding were not found.

Pharmacokinetic data suggest that excretion into breast milk would be significant. However, it is considered safe for treatment of parasite infections like Amebiasis in children, with a dosage for children weighing over 5 kg that has been established by the manufacturer.

It is a medication included in a same group and similar properties of Metronidazole.

Alternatives

We do not have alternatives for Secnidazole since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • سيكنيدازول (Arabic)
  • Секнидазол (Cyrillic)
  • 塞克硝唑 (Chinese)
  • セクニダゾール (Japanese)
  • C7 H11 N3 O3 (Molecular formula)

Drug trade names

References

  1. Rodríguez Grullón JM, Castellanos Nouel M, Romero Suero Y, Rodríguez Caro R. Eficacia del Secnidazol a dosis única. Acta Médica Dominicana 31(1):23-26 2011 Full text (link to original source) Full text (in our servers)
  2. Novag Secnidazol (Minovag) Ficha técnica 2011 Full text (in our servers)
  3. Aventis Pharma Secnidazol (Secnidal) Ficha técnica 2011 Full text (in our servers)
  4. Goto R, Mascie-Taylor CG, Lunn PG. Impact of anti-Giardia and anthelminthic treatment on infant growth and intestinal permeability in rural Bangladesh: a randomised double-blind controlled study. Trans R Soc Trop Med Hyg. 2009Abstract
  5. Gillis JC, Wiseman LR. Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis. Drugs. 1996Abstract
  6. Toppare MF, Kitapçi F, Senses DA, Yalcinkaya F, Kaya IS, Dilmen U. Ornidazole and secnidazole in the treatment of symptomatic intestinal amoebiasis in childhood. Trop Doct. 1994Abstract
  7. Sinuhaji AB, Lubis CP, Daulay HR, Hamid ED, Lubis IT, Jufri A, Sutanto AH. A double blind trial between metronidazole and secnidazole in acute amebic dysentery in children (preliminary report). Paediatr Indones. 1986Abstract