Sodium Citrate
Sodium salt of citric acid.
It is used rectally in enemas as it acts as an osmotic laxative and in bladder irrigations to dissolve clots. It has the alkalizing properties of urine, neutralizing gastric pH and is an anticoagulant.
Since the last update, we have not found published data on its excretion in breast milk.
Given the small amounts and route of administration, systemic absorption is practically nil (AEMPS 2013), so no significant excretion in breast milk is expected.
If absorbed, it is metabolized to bicarbonate.
Both sodium and bicarbonate are normal components of the body and are found in breastmilk at concentrations which are different to plasma (Allen 1991).
Alternatives
We do not have alternatives for Sodium Citrate since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Trisodium Citrate
Writings
- νάτριο κιτρικό (Greek)
- Цитрат Натрия Трёхзамещенный (Cyrillic)
- クエン酸ナトリウム (Japanese)
- C6H5Na3O7 (Molecular formula)
- C6H5Na3O7,2H2O (Molecular formula)
- Trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate (Chemical name)
- B05CB02 (ATC Code/s)
Drug trade names
References
- AEMPS. Micralax. Ficha técnica. 2013 Full text (in our servers)
- Allen JC, Keller RP, Archer P, Neville MC. Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation. Am J Clin Nutr. 1991Abstract