Is Sodium Cromoglicate compatible with breastfeeding? Do we have alternatives for Sodium Cromoglicate?

Sodium Cromoglicate

January 29, 2017 (Very Low Risk)

It is administered by inhalation for the prevention of asthma and atopic rhinitis, orally for food allergies and topically on dermatologic and ophthalmologic conditions.

At latest update relevant published data on excretion into breast milk were not found.

There is a consensus among experts and scientific societies on considering Sodium Chromoglycate as compatible while breastfeeding (Nelson 2001, National Asthma Education 2004, Powrie 2006) because of a minimal absorption and low plasma levels appearing in the mother (AEMPS 2013, Davis 2015).

The small dose used and low plasma absorption of most inhaled preparations (either buccal or nasal), topically apply as ophthalmologic or dermatologic preparations, make it unlikely any passage in a significant amount into breastmilk.

WHO List of Essential Medicines 2002: compatible while breastfeeding.

Alternatives

We do not have alternatives for Sodium Cromoglicate since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Cromolyn Sodium

Writings

  • χρωμογλυκικό νάτριο (Greek)
  • Натрий Кромоглициат (Cyrillic)
  • クロモグリク酸ナトリウム (Japanese)
  • C23H14Na2O11 (Molecular formula)

Drug trade names

References

  1. Davis C. Cromolyn. Drug Summary. 2015 Full text (in our servers)
  2. AEMPS. Cromoglicato. Ficha técnica. 2013 Full text (in our servers)
  3. Powrie RO, Larson L, Miller M. Managing asthma in expectant mothers. Treat Respir Med. 2006Abstract
  4. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. 2004 Full text (link to original source) Full text (in our servers)
  5. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Quick Reference from the Working Group Report on Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-12. 2004 Full text (link to original source) Full text (in our servers)
  6. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)