Is Tetanus Vaccine compatible with breastfeeding? Do we have alternatives for Tetanus Vaccine?

Tetanus Vaccine

July 1, 2015 (Very Low Risk)

Tetanus-bacillus toxoid.

Vaccines are usually compatible with breastfeeding either if they are formed by live, attenuated, inactivated, death strains or microorganism toxoid.

Except for rubella vaccine, they are not excreted into breast milk and do not cause harm to the infant. Yellow fever vaccine has a higher risk for harm effect on infants younger than 6 months old (Consult information on a particular vaccine at our web).

Breastfeeding may enhance antibody response to vaccines and cause fewer side effects as fever or anorexia.

Early postpartum period is appropriate to get mothers vaccinated against measles, rubella, mumps and varicella in case they were not immunized.

Breastfeeding mothers should be protected by providing recommended vaccination for adults.

Alternatives

We do not have alternatives for Tetanus Vaccine since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

References

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  2. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013Abstract Full text (link to original source) Full text (in our servers)
  3. Raney EC, El-Ibiary SY. Immunizations and pregnancy: an update for pharmacists. J Am Pharm Assoc. 2012Abstract Full text (in our servers)
  4. Perin MC, Schlindwein CF, de Moraes-Pinto MI, Simão-Gurge RM, de Mello Almada Mimica AF, Goulart AL, dos Santos AM. Immune response to tetanus booster in infants aged 15 months born prematurely with very low birth weight. Vaccine. 2012Abstract Full text (in our servers)
  5. Raney EC, El-Ibiary SY. Immunizations and pregnancy: an update for pharmacists. J Am Pharm Assoc (2003). 2012Abstract
  6. Gall SA. Prevention of pertussis, tetanus, and diphtheria among pregnant, postpartum women, and infants. Clin Obstet Gynecol. 2012Abstract
  7. National Center for Immunization and Respiratory Diseases. General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011Abstract Full text (in our servers)
  8. Halperin BA, Morris A, Mackinnon-Cameron D, Mutch J, Langley JM, McNeil SA, Macdougall D, Halperin SA. Kinetics of the antibody response to tetanus-diphtheria-acellular pertussis vaccine in women of childbearing age and postpartum women. Clin Infect Dis. 2011Abstract Full text (in our servers)
  9. Pisacane A, Continisio P, Palma O, Cataldo S, De Michele F, Vairo U. Breastfeeding and risk for fever after immunization. Pediatrics. 2010Abstract Full text (in our servers)
  10. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010Abstract Full text (link to original source) Full text (in our servers)
  11. Gruslin A, Steben M, Halperin S, Money DM, Yudin MH; SOGC. Immunization in pregnancy: No. 220, December 2008. Int J Gynaecol Obstet. 2009Abstract
  12. Gruslin A, Steben M, Halperin S, Money DM, Yudin MH, Boucher M, Cormier B, Ogilvie G, Paquet C, Steenbeek A, Van Eyk N, van Schalkwyk J, Wong T. Immunization in pregnancy. J Obstet Gynaecol Can. 2008Abstract
  13. Murphy TV, Slade BA, Broder KR, Kretsinger K, Tiwari T, Joyce PM, Iskander JK, Brown K, Moran JS; Advisory Committee on Immunization Practices (ACIP) Centers for Disease Control and Prevention (CDC). Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2008Abstract Full text (in our servers)
  14. Schmidt JV, Kroger AT, Roy SL. Report from the CDC. Vaccines in women. J Womens Health (Larchmt). 2004Abstract
  15. Tillett J. The use of vaccines in pregnancy. J Perinat Neonatal Nurs. 2004Abstract
  16. López-Alarcón M, Garza C, Habicht JP, Martínez L, Pegueros V, Villalpando S. Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization: possible roles of interleukin-1beta, tumor necrosis factor-alpha and leptin. J Nutr. 2002Abstract Full text (in our servers)
  17. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  18. Pabst HF, Spady DW, Pilarski LM, Carson MM, Beeler JA, Krezolek MP. Differential modulation of the immune response by breast- or formula-feeding of infants. Acta Paediatr. 1997Abstract
  19. Pabst HF. Immunomodulation by breast-feeding. Pediatr Infect Dis J. 1997Abstract
  20. [No authors listed] General recommendations on immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 1994Abstract Full text (in our servers)
  21. Hahn-Zoric M, Fulconis F, Minoli I, Moro G, Carlsson B, Böttiger M, Räihä N, Hanson LA. Antibody responses to parenteral and oral vaccines are impaired by conventional and low protein formulas as compared to breast-feeding. Acta Paediatr Scand. 1990Abstract