Is Triamcinolone Inhaled compatible with breastfeeding? Do we have alternatives for Triamcinolone Inhaled?

Triamcinolone Inhaled

October 11, 2017 (Very Low Risk)

A corticosteroid with a mainly glucocorticoid action and moderate anti-inflammatory effects (ATC D07AB), slightly higher than that of prednisolone (ATC D07AA).

Indicated inhaled use in the treatment of inflammatory diseases of the respiratory system: bronchitis, asthma, rhinitis, etc.

This comment is about inhaled triamcinolone.

Since the last update we have not found published data about its excretion in breast milk.

After inhaled administration, the bioavailability is 25% (Argenti 1999) and the plasma levels reached are clinically insignificant (Zaborny 1992).

There is consensus among experts that, in general, neither systemic corticoids nor inhaled ones present a breastfeeding contraindication (National Asthma Education 2004).

Corticoids are of commonally used in pediatrics and have no side effects when they are used in isolation or in short-term treatments.


See below the information of these related products:

Alternatives

We do not have alternatives for Triamcinolone Inhaled since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Fluoxiprednisolonum

Writings

  • R03BA06 (ATC Code/s)

Drug trade names

References

  1. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. 2004 Full text (link to original source) Full text (in our servers)
  2. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Quick Reference from the Working Group Report on Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-12. 2004 Full text (link to original source) Full text (in our servers)
  3. Argenti D, Shah B, Heald D. A pharmacokinetic study to evaluate the absolute bioavailability of triamcinolone acetonide following inhalation administration. J Clin Pharmacol. 1999Abstract
  4. Zaborny BA, Lukacsko P, Barinov-Colligon I, Ziemniak JA. Inhaled corticosteroids in asthma: a dose-proportionality study with triamcinolone acetonide aerosol. J Clin Pharmacol. 1992Abstract