Tyrothricin
Polypeptide with antibacterial properties which is isolated through fermentation of Bacillus brevis. It contains a mixture of Gramicidin and Tyrocidine.
Topically used on skin and mouth infections, often associated with benzocaine.
It is highly toxic when systemically used. It has been withdrawn from the market in some countries due to lack of therapeutic effectiveness.
Given its negligible systemic absorption and high molecular weight, excretion into breastmilk is highly unlikely.
Do not apply on the breast to prevent ingestion by the infant.
Alternatives
We do not have alternatives for Tyrothricin since it is relatively safe.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Writings
- τυροτριχίνη (Greek)
- تيروثريسين (Arabic)
- Тиротрицин (Cyrillic)
- 短杆菌素 (Chinese)
- チロトリシン (Japanese)
- C65H85N11O13 (Molecular formula)
Drug trade names
References
- WHO Pharmaceuticals Newsletter. 2005 Full text (link to original source) Full text (in our servers)