Is Vitamin B1 Substances compatible with breastfeeding? Do we have alternatives for Vitamin B1 Substances?

Vitamin B1 Substances

July 11, 2016 (Very Low Risk)

Thiamine or Vitamin B1 is a water soluble vitamin. In addition to Thiamine, other chemical compounds with similar activity: Acetiamine, Benfotiamine, Bisbentiamine, Bisbutiamina, Cetotiamina, Cicotiamina, Cocarboxylase, Fursultiamine, Monofosfotiamina, Octotiamine, Pyrophosphotiamine, Prosultiamine and Sulbutiamine.
It is essential for the metabolism of carbohydrate nutrients.

Its deficiency causes severe neuromuscular and cardiac symptoms known as Beriberi and Wernicke-Korsakoff disease. Thiamine deficiency is common among disadvantaged populations in Southeast Asia (predominantly consumers of refined rice), other malnourished people (refugees, low socioeconomic status ...) and chronic alcohol consumption.
Beriberi of childhood, both infants and children, may arise from breastfeeding by Thiamine deficient mothers. Reportedly, several severe cases have occured after feeding the babies with artificial formulas that were not supplemented with vitamin B1.

Daily allowance is higher during pregnancy and lactation (1.5 mg / day) which is readily obtained through a varied diet with adequate content of whole grains, legumes, nuts, eggs and lean meat.
Thiamine is excreted in breast milk and gradually increases with time, being lower in colostrum (28 ng / mL) and transitional milk than in mature milk (180 ng / mL). The concentration is lower in milk from mothers of preterm (90 ng / mL).

Taking vitamin supplementation is not required if diet and nutritional status are adequate. Supplementation does not increase levels in milk of well-nourished women, but of those with a low nutritional status. The supplementation of group B vitamins and C and E vitamins to HIV positive mothers improves the weight growth of their breasted babies.
There is no evidence of their effectiveness in improving athletic performance, lack of appetite, sores, stress, fatigue or aging.
Toxicity linked to excessive consumption of thiamine is not known.

WHO List of Essential Medicines 2002: compatible with breastfeeding.
American Academy of Pediatrics: usually compatible with breastfeeding

Alternatives

We do not have alternatives for Vitamin B1 Substances since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Acetiamine Hydrochloride
  • Aneurine Hydrochloride
  • Benfotiamine
  • Bisbentiamine
  • Bisibutiamine
  • Cetotiamine Hydrochloride
  • Cocarboxylase
  • Cycotiamine
  • Fursultiamine
  • Monophosphothiamine
  • Octotiamine
  • Prosultiamine
  • Sulbutiamine
  • Thiamine
  • Thiamine Hydrochloride
  • Thiamine Nitrate
  • Thiamine Pyrophosphate

Writings

  • θειαμίνη (Greek)
  • سولبوتيامين (Arabic)
  • كوكاربوكسيلاز (Arabic)
  • Витамины Группы B1 (Cyrillic)
  • Кетотиамина (Cyrillic)
  • Кокарбоксилаза (Cyrillic)
  • Сульбутиамин (Cyrillic)
  • Тиамина (Cyrillic)
  • 舒布硫胺 (Chinese)
  • 辅羧酶 (Chinese)
  • チアミン (Japanese)
  • セトチアミン (Japanese)
  • ビスイブチアミン (Japanese)
  • コカルボキシラーゼ (Japanese)
  • C12H17ClN4OS (Molecular formula)

Drug trade names

References

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