Is Zaleplon compatible with breastfeeding? Do we have alternatives for Zaleplon?

Zaleplon

March 27, 2015 (Very Low Risk)

Used for treatment of insomnia.

It is excreted in non-significant clinical amount into breast milk.

Foods with high fat content may delay absorption by the gut. A low oral bioavailability decreases the pass of it from the mother's milk to the infant's plasma, except in prematures or in the early neonatal period, when a higher intestinal absorption may occur.

Not commercially available in Spain

Alternatives

We do not have alternatives for Zaleplon since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • ザレプロン
  • زاليبلون
  • ζαλεπλόνη
  • Залеплон
  • 扎来普隆

Drug trade names

References

  1. FDA. Zaleplon. Drug Summary. 2005 Full text (in our servers)
  2. Drover DR. Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives: zaleplon, zolpidem and zopiclone. Clin Pharmacokinet. 2004Abstract
  3. Osakidetza. Zaleplon. Ficha técnica. 2001 Full text (in our servers)
  4. Darwish M, Martin PT, Cevallos WH, Tse S, Wheeler S, Troy SM. Rapid disappearance of zaleplon from breast milk after oral administration to lactating women. J Clin Pharmacol. 1999Abstract