Is Zanamivir compatible with breastfeeding? Do we have alternatives for Zanamivir?

Zanamivir

January 29, 2014 (Very Low Risk)

Prophylaxis and treament of Influenza virus disease.

A low excrection into breast milk and low oral biodisponibility, both characteristics make it even safer while breastfeeding.

No adverse effects have been shown in breastfed infants.

Alternatives

We do not have alternatives for Zanamivir since it is relatively safe.

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. Skalli S, Ferreira E, Bussières JF, Allenet B. [Influenza A/H1N1v 2009 during pregnancy and breastfeeding: which antiviral to choose?]. Ann Pharm Fr. 2010Abstract
  2. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010Abstract Full text (link to original source) Full text (in our servers)
  3. Tanaka T, Nakajima K, Murashima A, Garcia-Bournissen F, Koren G, Ito S. Safety of neuraminidase inhibitors against novel influenza A (H1N1) in pregnant and breastfeeding women. CMAJ. 2009Abstract Full text (in our servers)
  4. Academy of Breastfeeding Medicine. Breastfeeding / Swine Flu Recommendations for Physicians from the Academy of Breastfeeding Medicine For immediate release (ABM) 2009 Full text (in our servers)
  5. PDR Zanamivir Drug Summary 2009 Full text (in our servers)
  6. Agencia Española del Medicamento Uso de Oseltamivir y Zanamivir en niños de cualquier edad, en mujeres gestantes y mujeres en periodo de lactancia y en personas con problemas de deglución.\ Nota Informativa 2009 Full text (in our servers)
  7. Cass LM, Efthymiopoulos C, Bye A. Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers. Clin Pharmacokinet. 1999Abstract