Is Acarbose compatible with breastfeeding? Do we have alternatives for Acarbose?

Acarbose

August 6, 2017 (Very Low Risk)

Alpha-glucosidase inhibitor which acts within the gastrointestinal tract without being absorbed, reducing intestinal absorption of glucose. Very low risk of hypoglycemia in monotherapy.

Since the last update we have not found any published data on its excretion in breast milk.

Its pharmacokinetic data (moderately elevated molecular weight and very low intestinal absorption) make it unlikely that it would pass to breast milk in significant amounts (Serrano 2014, Everett 1997).

Diet, exercise, and breastfeeding improve blood sugar levels.


See below the information of this related product:

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Akarbos

Writings

  • Ακαρβόζη (Greek)
  • أكاربوز (Arabic)
  • Акарбоза (Cyrillic)
  • 阿卡波糖 (Chinese)
  • アカルボース (Japanese)
  • C25H43NO18 (Molecular formula)

References

  1. Davis C. Acarbose. Drug Summary. 2015 Full text (in our servers)
  2. Serrano Aguayo P, García de Quirós Muñoz JM, Bretón Lesmes I, Cózar León MV. Tratamiento de enfermedades endocrinológicas durante la lactancia. [Endocrinologic diseases management during breastfeeding.] Med Clin (Barc). 2015Abstract
  3. AEMPS. Acarbosa. Ficha técnica. 2009 Full text (in our servers)
  4. Everett JA. Use of oral antidiabetic agents during breastfeeding. J Hum Lact. 1997Abstract
  5. Ahr HJ, Krause HP, Siefert HM, Steinke W, Weber H. Pharmacokinetics of acarbose. Part II: Distribution to and elimination from tissues and organs following single or repeated administration of [14C]acarbose to rats and dogs. Arzneimittelforschung. 1989Abstract
  6. Ahr HJ, Boberg M, Krause HP, Maul W, Müller FO, Ploschke HJ, Weber H, Wünsche C. Pharmacokinetics of acarbose. Part I: Absorption, concentration in plasma, metabolism and excretion after single administration of [14C]acarbose to rats, dogs and man. Arzneimittelforschung. 1989Abstract