Is Amiloride compatible with breastfeeding? Do we have alternatives for Amiloride?

Amiloride

August 12, 2014 (Low Risk)

Potassium-sparing diuretic.

On latest update relevant data on breastfeeding were not found.

Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting and loop-acting effect) may inhibit lactation. Use the lower dose as possible especially during the first postnatal month.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

  1. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  2. Vidt DG. Mechanism of action, pharmacokinetics, adverse effects, and therapeutic uses of amiloride hydrochloride, a new potassium-sparing diuretic. Pharmacotherapy. 1981Abstract