Is Betahistine compatible with breastfeeding? Do we have alternatives for Betahistine?

Betahistine

October 15, 2014 (Low Risk)

Histamine analogue drug which is used for treatment of Meniere's vertigo

At latest update, relevant information on excretion into breast milk was not found.

Because of pharmacokinetic data it is likely excretion into breast milk though from low plasma levels, usually below the detection threshold (100 pg/mL)

Side-effects likely would be mild: nausea, dyspepsia, head ache.

Consider other better known options, otherwise follow-up the child for symptoms like nausea, crying and fussiness.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • ベタヒスチン
  • بيتاهيستين
  • Βηταϊστίνη
  • Бетагистин
  • 倍他司汀

References

  1. Schaaf H. Cochrane analysis on betahistine omitted. Dtsch Arztebl Int. 2013Abstract Full text (link to original source) Full text (in our servers)
  2. Monzani D, Barillari MR, Alicandri Ciufelli M, Aggazzotti Cavazza E, Neri V, Presutti L, Genovese E. Effect of a fixed combination of nimodipine and betahistine versus betahistine as monotherapy in the long-term treatment of Ménière's disease: a 10-year experience. Acta Otorhinolaryngol Ital. 2012Abstract Full text (link to original source) Full text (in our servers)
  3. Betahistina. Ficha técnica. 2011 Full text (in our servers)
  4. Betahistine. Drug Summary. 2010 Full text (in our servers)
  5. Della Pepa C, Guidetti G, Eandi M. Betahistine in the treatment of vertiginous syndromes: a meta-analysis. Acta Otorhinolaryngol Ital. 2006Abstract Full text (link to original source) Full text (in our servers)
  6. James AL, Burton MJ. Betahistine for Menière's disease or syndrome. Cochrane Database Syst Rev. (rev. 2011) 2001Abstract Full text (link to original source) Full text (in our servers)