Is Bisacodyl compatible with breastfeeding? Do we have alternatives for Bisacodyl?
Bisacodyl
January 29, 2017 (Very Low Risk)
A laxative which acts as stimulant in the intestine.
A low oral bioavailability due to minimal intestinal absorption that renders the plasma levels being very low would explain the non passage to breast milk observed (undetectable levels: Friedrich 2011).
On prevention or treating constipation, it is essential a balanced and rich-in-fiber diet along with a lot of fluids and physical exercise.
Alternatives
- Lactulose (Very Low Risk)
- Liquid Paraffin (Low Risk probable)
- Docusate (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Writings
- Βισακοδύλη (Greek)
- بيساكوديل (Arabic)
- Бисакодил (Cyrillic)
- 比沙可啶 (Chinese)
- ビサコジル (Japanese)
- C22H19NO4 (Molecular formula)
Drug trade names
- Alophen™
- Alsylax™
- Bisa-Lax™
- Bisacolax™
- Bisalax™
- Correctol™
- Dulcolan™
- Dulcolax (Дульколакс)™
- Dulcolax (乐可舒)™
- Dulcolaxo™
- Dulcolax™
- Fleet Laxative™
- Gentlax™
- Laxabixal™
- Laxamin™
- Laxans™
- Laxodyl™
- Mediolax™
- Modane™
- Modaton™
- Moderlax™
- Pyrilax™
- Toilax™
- Tractoduo™
- Ultralax™
- БІСАКОДИЛ
- БІСАКОДИЛ ГРІНДЕКС
- БІСАКОДИЛ-ДАРНИЦЯ
- БІСАКОДИЛ-ФАРМЕКС
References
- Gharehbaghi K, Gharehbaghi DR, Wierrani F, Sliutz G. [Treatment of Chronic Functional Constipation during Pregnancy and Lactation]. Z Geburtshilfe Neonatol. 2016Abstract
- Müller-Lissner S. Pharmacokinetic and pharmacodynamic considerations for the current chronic constipation treatments. Expert Opin Drug Metab Toxicol. 2013Abstract
- AEMPS. Bisacodilo. Ficha técnica. 2012 Full text (in our servers)
- Friedrich C, Richter E, Trommeshauser D, de Kruif S, van Iersel T, Mandel K, Gessner U. Absence of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel-group, multiple-dose study in healthy lactating women. Drug Metab Pharmacokinet. 2011Abstract Full text (link to original source) Full text (in our servers)
- Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006Abstract Full text (link to original source) Full text (in our servers)
- Müller-Lissner S. [Side effects of laxatives]. Z Gastroenterol. 1992Abstract
- Anderson PO. Drug use during breast-feeding. Clin Pharm. 1991Abstract
- Vorherr H. Drug excretion in breast milk. Postgrad Med. 1974Abstract